Regenerative skin treatments all promise the same thing — your skin, rebuilt with growth factors. But the three you'll hear about at Privé Aesthetics in Dallas — PRP, PRF, and Ariessence Pure PDGF — get there in genuinely different ways. Here's how they actually differ, and how we choose between them.
"Growth factors" is the thread connecting all three: signaling proteins that tell your skin to build collagen, improve tone, and repair. Where PRP, PRF, and PDGF diverge is in where the growth factors come from and how they're delivered. That difference is the whole decision.
PRP — platelet-rich plasma
PRP is the original, and it's autologous — made from your own blood. We draw a small sample, spin it to concentrate the platelets (which carry growth factors), and use that plasma in the skin, often paired with microneedling (the "vampire facial") or placed in targeted areas. It's a proven, natural approach. Its main limitation is variability: the concentration and potency depend on your blood that day, your hydration, and your physiology.
PRF — platelet-rich fibrin
PRF is the next-generation evolution of PRP, and also autologous. The key difference is in the spin: PRF is processed without anticoagulant and at a gentler speed, which lets it form a natural fibrin matrix — a scaffold that traps the platelets and white blood cells and releases growth factors slowly, over days, rather than all at once. The result is typically a richer growth-factor payload with more sustained release than PRP. When patients ask "PRP or PRF," PRF is usually the more potent of the two autologous options.
Ariessence Pure PDGF — the standardized option
Here's where the third option is genuinely different. Ariessence Pure PDGF is not made from your blood — it's a purified, lab-derived form of platelet-derived growth factor (PDGF), one of the most important signaling proteins in skin repair. At Privé, we apply it topically, immediately after SkinPen microneedling — the fresh micro-channels carry it into the skin. Because it's standardized and pure, every treatment delivers the same concentration of that growth factor, with none of the day-to-day variability of an autologous draw. It's the centerpiece of our signature regenerative protocol.
How we actually choose
It comes down to what you value. Choose PRF (or PRP) if you specifically want an autologous, all-your-own-biology treatment and like the idea of using nothing but your own blood — PRF being the more potent, sustained-release of the two. Choose Ariessence PDGF with SkinPen if you want consistency and standardized potency, no blood draw, and the specific PDGF pathway that our protocol is built around. They're not mutually exclusive over time — but for a given goal, that's the fork.
A note on how Privé uses them
All three live in our regenerative category, and all three pair naturally with microneedling, which opens the channels that let growth factors work. Our publicly signature pathway is topical Ariessence PDGF with SkinPen — standardized, clean, and reproducible. PRP and PRF remain excellent autologous options for patients who prefer their own biology. At consultation we match the approach to your goal, your skin, and your preference for autologous vs. standardized.
What they cost
At Privé, the autologous options start at $599 (EZ PRF), and our SkinPen protocol starts at $225, with PRP adding $200 and Ariessence PDGF adding $300 to a microneedling session. We map the right combination — and the total — at consultation.
Frequently asked
What is the difference between PRP and PRF?
Both are autologous — made from your own blood. PRF is the next-generation version: it's processed without anticoagulant and at a gentler speed, forming a fibrin matrix that releases growth factors slowly over days rather than all at once. PRF typically delivers a richer, more sustained growth-factor payload than PRP.
How is Ariessence Pure PDGF different from PRP and PRF?
PRP and PRF come from your own blood, so potency varies with your physiology that day. Ariessence Pure PDGF is a purified, lab-derived growth factor — standardized, so every treatment delivers the same concentration with no blood draw. At Privé it's applied topically right after SkinPen microneedling.
Is PRP or PRF better?
For most goals, PRF is the more potent of the two autologous options because its fibrin matrix releases growth factors gradually and it carries a richer payload. PRP remains a proven, effective option. We match the choice to your goal at consultation.
How is Ariessence Pure PDGF applied?
At Privé, Ariessence Pure PDGF is applied topically, immediately after SkinPen microneedling — the fresh micro-channels carry it into the skin. It's the centerpiece of our signature regenerative protocol.
How much do PRP, PRF, and the PDGF protocol cost in Dallas at Privé?
The autologous options start at $599 (EZ PRF). Our SkinPen protocol starts at $225, with PRP adding $200 and Ariessence PDGF adding $300 to a microneedling session. We map the right combination and total at consultation.
Which regenerative treatment should I choose?
Choose PRF (or PRP) if you want an all-autologous, your-own-biology treatment — PRF being the more potent. Choose Ariessence PDGF with SkinPen if you want standardized potency, no blood draw, and the specific PDGF pathway our protocol is built around.